Tetrapyrroles and derivatives
Abcam Dorsomorphin (Compound C), AMP-kinase inhibitor, 5MG
MW 399.5 Da, Purity >99%. Potent, selective and reversible inhibitor of AMP-kinase (Ki = 109 nM). Inhibits AMPK activation induced by AICAR (ab120358) and metformin (ab120847). Selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Does not affect ZAPK, SYK, PKCθ, PKA and JAK3. Cell-permeable. Also available in a water soluble form (Dorsomorphin dihydrochloride - ab144821).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Nocodazole, Microtubule inhibitor, 10MG
MW 301.32 Da, Purity >98%. Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.
The product is subject to the following: Abcam Restricted Use Statement
Abcam A 943931 dihydrochloride, H4 receptor antagonist, 50MG
MW 368.3 Da, Purity >99%. Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam x estospongin C, IP3 receptor antagonist, 10UG
MW 446.72 g/mol, Purity >90%. Potent, selective, reversible IP₃ receptor antagonist (IC₅₀ = 350 nM). Inhibits IP₃-mediated Ca²+ release from ER and SR. 30-Fold selectivity over ryanodine receptor. Inhibits voltage-dependent Ca²+ and K+ channels at higher concentrations. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam UDP-glucose, Highly P2Y14 agonist, 100MG
MW 610.27 Da. Highly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Necrostatin-1, necroptosis inhibitor, 10MG
MW 259.33 Da, Purity >99%. Potent, specific necroptosis inhibitor (EC₅₀ = 490 nM). Selective allosteric inhibitor of death domain receptor-associated adaptor kinase RIP1 in vitro (EC₅₀ = 182 nM). Caspase independent, programmed necrosis pathway.
The product is subject to the following: Abcam Restricted Use Statement
Abcam x estospongin C, IP3 receptor antagonist, 50UG
MW 446.72 g/mol, Purity >90%. Potent, selective, reversible IP₃ receptor antagonist (IC₅₀ = 350 nM). Inhibits IP₃-mediated Ca²+ release from ER and SR. 30-Fold selectivity over ryanodine receptor. Inhibits voltage-dependent Ca²+ and K+ channels at higher concentrations. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam LY 294002, PI3-kinase inhibitor, 25MG
MW 307.3 Da, Purity >99%. A highly selective inhibitor of phosphatidylinositol 3-kinase (IC₅₀ = 1.4 μM). Selective over a range of other kinases including protein kinase C, protein kinase A, MAPK and PI4- kinase (IC₅₀ > 50 μM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Endothelin-1 (human, porcine), Vasoconstrictor peptide, 500UG
MW 2491.9 Da. Endothelin-1 (human, porcine), Vasoconstrictor peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam x anomeline o x alate, M1 muscarinic acetylcholine receptor agonist, 10MG
MW 371.5 Da, Purity >99%. Functionally preferring M₁ muscarinic acetylcholine receptor agonist (pKi values are 7.1 (M₁), 6.9 (M₂), 7.4 (M₃), 7.7 (M₄) and 7.4 (M₅)). Able to cross blood-brain barrier. Displays antipsychotic activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam C59, Wnt Antagonist, Wnt signaling pathway inhibitor, 5MG
MW 379.5 Da, Purity >97%. Potent Wnt signaling pathway inhibitor. Inhibits porcupine (PORCN) required for Wnt palmitoylation, secretion, and biological activity. Inhibits Wnt-mediated transcription (IC₅₀ = 74 pM) and cell proliferation. Active in vivo..
The product is subject to the following: Abcam Restricted Use Statement
Abcam E x endin (9-39) amide, GLP-1 receptor antagonist, 1MG
MW 3369.8 Da, Purity >98%. Exendin (9-39) amide, GLP-1 receptor antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Protoporphyrin IX (PPIX) S5145-1g
Protoporphyrin IX (PPIX) is a heterocyclic organic compound which consists of four pyrrole rings and is the final intermediate in the heme biosynthetic pathway
Medchemexpress LLC HY-B0754A 100mg , Hematoporphyrin (dihydrochloride) Hematoporphyrin IX dihydrochloride CAS:17696-69-4 Purity:98%
Medchemexpress, HY-B0754A 100mg Hematoporphyrin (dihydrochloride) Hematoporphyrin IX dihydrochloride CAS:17696-69-4 Formula:C34H40Cl2N4O6 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Frontier Specialty Chemicals 1G MESO-TETRA(4-PYRIDYL)PORPHI
meso-Tetra(4-pyridyl)porphine; CAS: 16834-13-2; 1g