Tetrapyrroles and derivatives
Medchemexpress LLC Methylcobalamin | 13422-55-4 | 99.0% | 100 MG
Methylcobalamin is a form of vitamin B12, where a methyl group replaces cyanide. It features an octahedral cobalt(III) center and can be obtained as bright red crystals. Notable for containing metal-alkyl bonds, it is physiologically equivalent to vitamin B12. Methylcobalamin is used to treat conditions from vitamin B12 deficiency, including pernicious anemia, peripheral neuropathy, and diabetic neuropathy, and as an initial treatment for amyotrophic lateral sclerosis.
- Form of vitamin B12
- Features an octahedral cobalt(III) center
- Can be obtained as bright red crystals
- Contains metal-alkyl bonds
- Treats vitamin B12 deficiency
- Used for pernicious anemia
- Treats peripheral neuropathy
- Treats diabetic neuropathy
- Initial treatment for amyotrophic lateral sclerosis
- Classified as a human endogenous metabolite
Medchemexpress LLC Methylcobalamin (standard) | 13422-55-4 | 96.8% | 100 MG
Methylcobalamin (Standard) is an analytical standard, also known as Mecobalamin (Standard) or CH3-B12 (Standard). It serves as a reference standard for assay and is intended for research and analytical applications. It is commonly utilized in qualitative, quantitative, and methodological research experiments.
- Used as a reference standard for assay
- Suitable for qualitative, quantitative, and methodological research experiments
- Compatible with techniques such as HPLC, GC, and MS
- Intended for research and analytical applications only
Sigma Aldrich Fine Chemicals Biosciences Methylcobalamin United Sta50MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from equine heart suitable for GFC marker, BioReagent | 9007-43-6 | MFCD00130890 | 1VL
Cytochrome c from equine heart suitable for GFC marker, BioReagent | 9007-43-6 | MFCD00130890 | 1VL
![eMolecules Medchem Express / Hematoporphyrin monomethyl ether / 5mg / 705860738 / HY-134990 / / 148471-91-4 / [null] / 1225.454 / C70H80N8O12](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502465141.JPG-250.jpg)
eMolecules Medchem Express / Hematoporphyrin monomethyl ether / 5mg / 705860738 / HY-134990 / / 148471-91-4 / [null] / 1225.454 / C70H80N8O12
Medchem Express / Hematoporphyrin monomethyl ether / 5mg / 705860738 / HY-134990 / / 148471-91-4 / [null] / 1225.454 / C70H80N8O12
Medchemexpress LLC Protoporphyrin IX (Standard) | 553-12-8 | 96.1% | 50 MG
Protoporphyrin IX (Standard) serves as an analytical reference standard for diverse research and analytical applications. It functions as a key intermediate in the heme biosynthetic pathway, acting as both a radiation sensitizer-boosting reactive oxygen species (ROS) generation and inducing DNA damage even in hypoxic states-and a photosensitizer, undergoing photobleaching upon light exposure.
- Enhances ROS generation and induces DNA damage.
- Undergoes photobleaching through direct degradation by light irradiation.
- Accumulates in tumor cells after 5-aminolevulinic acid (5-ALA) administration.
- Causes selective improvement of basal cell carcinoma when activated by red fluorescence.
- Promising for research into sonodynamic and photodynamic agents for various cancers.
- Used in qualitative, quantitative, and methodological research experiments.
- Ideal for applications in HPLC, GC, and MS.
Medchemexpress LLC Protoporphyrin IX (disodium) | 50865-01-5 | 96.5% | 25 MG
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway. It acts as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. This product is promising for research of sonodynamic and photodynamic agents for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Final intermediate in the heme biosynthetic pathway
- Acts as a radiation sensitizer
- Enhances ROS generation and induces DNA damage
- Functions as a photosensitizer
- Undergoes photobleaching by light irradiation
- Accumulates in tumor cells after 5-aminolevulinic acid administration
- Causes selective improvement of basal cell carcinoma
- Promising for research into sonodynamic and photodynamic agents for various cancers
Medchemexpress LLC Zinc protoporphyrin (Zn(II)-protoporphyrin IX) | 15442-64-5 | 99.9% | 626.02 g/mol | C34H32N4O4Zn | 1 ML
Zinc protoporphyrin (Zn(II)-protoporphyrin IX) is a research reagent that acts as a competitive heme oxygenase-1 (HO-1) inhibitor and a biomarker for iron-deficiency screening. It is supplied as a ready-to-use 10 mM solution in DMSO and as solid preparations for laboratory use. Typical applications include cellular assays, mechanistic studies, and in vivo screening.
- Ready-to-use 10 mM solution in DMSO.
- Also available as solid in multiple mass sizes.
- Competitive heme oxygenase-1 (HO-1) inhibitor for research.
- Used as a screening marker for iron deficiency in vivo.
- High purity (approximately 99.9%).
- Molecular weight 626.02 g/mol; formula C34H32N4O4Zn.
- Includes product data sheet and SDS for handling information.
Enzo Life Sciences Zinc(II) Protoporphyrin IX (100mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Appearance: Dark solid. Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.